Is Antibiotic Therapy Necessary after Emergency Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis?

Background: While preoperative antibiotic therapy is standard to prevent surgical site infections in acute calculous cholecystitis, prescribing antibiotics after discharge controversial. This study aimed investigate the effect of administration prescription on infections.
 Methods: Data from patients who underwent emergency laparoscopic cholecystectomy for cholecystitis between January 2018 and February 2020 were retrospectively reviewed. Those with a decompensated systemic disease, those converted open cholecystectomy, stage 3 cholecystostomy excluded. Ampicillin-sulbactam 1 g was administered parenterally three times day before surgery.
 The divided into two groups according their prescriptions: given (AB group) not (NA group). primary outcome development Results: 107 AB group 109 NA group. Surgical infection developed 29 (13.4%) patients, 11 (10.3%) group, 18 (16.5%) No significant difference found regarding rate (p>0.05). In logistic regression analysis, obesity risk factor Conclusions: Failure prescribe ampicillin-sulbactam discharged surgery does increase infections. However, obese may reduce Keywords: infections,